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Aβ(43) is neurotoxic and primes aggregation of Aβ(40) in vivo

The involvement of Amyloid-β (Aβ) in the pathogenesis of Alzheimer’s disease (AD) is well established. However, it is becoming clear that the amyloid load in AD brains consists of a heterogeneous mixture of Aβ peptides, implying that a thorough understanding of their respective role and toxicity is...

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Detalles Bibliográficos
Autores principales: Burnouf, Sylvie, Gorsky, Marianna Karina, Dols, Jacqueline, Grönke, Sebastian, Partridge, Linda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469414/
https://www.ncbi.nlm.nih.gov/pubmed/25862636
http://dx.doi.org/10.1007/s00401-015-1419-y