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Aβ(43) is neurotoxic and primes aggregation of Aβ(40) in vivo
The involvement of Amyloid-β (Aβ) in the pathogenesis of Alzheimer’s disease (AD) is well established. However, it is becoming clear that the amyloid load in AD brains consists of a heterogeneous mixture of Aβ peptides, implying that a thorough understanding of their respective role and toxicity is...
Autores principales: | Burnouf, Sylvie, Gorsky, Marianna Karina, Dols, Jacqueline, Grönke, Sebastian, Partridge, Linda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469414/ https://www.ncbi.nlm.nih.gov/pubmed/25862636 http://dx.doi.org/10.1007/s00401-015-1419-y |
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