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Combination of Id2 Knockdown Whole Tumor Cells and Checkpoint Blockade: A Potent Vaccine Strategy in a Mouse Neuroblastoma Model

Tumor vaccines have held much promise, but to date have demonstrated little clinical success. This lack of success is conceivably due to poor tumor antigen presentation combined with immuno-suppressive mechanisms exploited by the tumor itself. Knock down of Inhibitor of differentiation protein 2 (Id...

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Detalles Bibliográficos
Autores principales: Chakrabarti, Lina, Morgan, Clifford, Sandler, Anthony D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469424/
https://www.ncbi.nlm.nih.gov/pubmed/26079374
http://dx.doi.org/10.1371/journal.pone.0129237