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Altered cytotoxicity of ROS-inducing compounds by sodium pyruvate in cell culture medium depends on the location of ROS generation

Induction of oxidative stress by drugs and other xenobiotics is an important mechanism of cytotoxicity. However, in vitro studies on the relationship between oxidative stress and cytotoxicity in cultured cells is frequently complicated by the fact that cell culture medium components affect reactive...

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Detalles Bibliográficos
Autores principales: Kelts, Jessica L, Cali, James J, Duellman, Sarah J, Shultz, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469600/
https://www.ncbi.nlm.nih.gov/pubmed/26090316
http://dx.doi.org/10.1186/s40064-015-1063-y