Combination of an Antigen-Specific Therapy and an Immunomodulatory Treatment to Simultaneous Block Recurrent Autoimmunity and Alloreactivity in Non-Obese Diabetic Mice

Restoration of endogenous insulin production by islet transplantation is considered a curative option for patients with type 1 diabetes. However, recurrent autoimmunity and alloreactivity cause graft rejection hindering successful transplantation. Here we tested whether transplant tolerance to allog...

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Detalles Bibliográficos
Autores principales: Fousteri, Georgia, Jofra, Tatiana, Di Fonte, Roberta, Battaglia, Manuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469694/
https://www.ncbi.nlm.nih.gov/pubmed/26080071
http://dx.doi.org/10.1371/journal.pone.0127631

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469694/
https://www.ncbi.nlm.nih.gov/pubmed/26080071
http://dx.doi.org/10.1371/journal.pone.0127631

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