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Different toxic effects of YTX in tumor K-562 and lymphoblastoid cell lines

Yessotoxin (YTX) modulates cellular phosphodiesterases (PDEs). In this regard, opposite effects had been described in the tumor model K-562 cell line and fresh human lymphocytes in terms of cell viability, cyclic adenosine 3',5'-cyclic monophosphate (cAMP) production and protein expression...

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Detalles Bibliográficos
Autores principales: Fernández-Araujo, Andrea, Sánchez, Jon A., Alfonso, Amparo, Vieytes, Mercedes R., Botana, Luis M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469822/
https://www.ncbi.nlm.nih.gov/pubmed/26136685
http://dx.doi.org/10.3389/fphar.2015.00124