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Different toxic effects of YTX in tumor K-562 and lymphoblastoid cell lines
Yessotoxin (YTX) modulates cellular phosphodiesterases (PDEs). In this regard, opposite effects had been described in the tumor model K-562 cell line and fresh human lymphocytes in terms of cell viability, cyclic adenosine 3',5'-cyclic monophosphate (cAMP) production and protein expression...
Autores principales: | Fernández-Araujo, Andrea, Sánchez, Jon A., Alfonso, Amparo, Vieytes, Mercedes R., Botana, Luis M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469822/ https://www.ncbi.nlm.nih.gov/pubmed/26136685 http://dx.doi.org/10.3389/fphar.2015.00124 |
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