Structural Identification of a Non-Glycosylated Variant at Ser126 for O-Glycosylation Site from EPO BRP, Human Recombinant Erythropoietin by LC/MS Analysis

A variant peak was detected in the analysis of RP-HPLC of rHu-EPO, which has about 7% relative content. Fractions of the main and the variant peaks were pooled separately and further analyzed to identify the molecular structure of the variant peak. Total mass analysis for each peak fraction using ES...

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Detalles Bibliográficos
Autores principales: Byeon, Jaehee, Lim, Yu-Ri, Kim, Hyong-Ha, Suh, Jung-Keun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469907/
https://www.ncbi.nlm.nih.gov/pubmed/26013384
http://dx.doi.org/10.14348/molcells.2015.2256