Cargando…

Complement regulator CD46: genetic variants and disease associations

Membrane cofactor protein (MCP; CD46) is an ubiquitously expressed complement regulatory protein that protects host cells from injury by complement. This type-I membrane glycoprotein serves as a cofactor for the serine protease factor I to mediate inactivation of C3b and C4b deposited on host cells....

Descripción completa

Detalles Bibliográficos
Autores principales: Liszewski, M. Kathryn, Atkinson, John P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4469999/
https://www.ncbi.nlm.nih.gov/pubmed/26054645
http://dx.doi.org/10.1186/s40246-015-0029-z