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A transient resistance to blood-stage malaria in interferon-γ-deficient mice through impaired production of the host cells preferred by malaria parasites

IFN-γ plays both pathological and protective roles during blood-stage malaria. One of its pathological roles is its contribution to anemia by suppressing erythropoiesis. Here, to evaluate the effects of IFN-γ-mediated alterations in erythropoiesis on the course of malaria infection, mice deficient i...

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Detalles Bibliográficos
Autores principales: Okada, Hiroko, Suzue, Kazutomo, Imai, Takashi, Taniguchi, Tomoyo, Shimokawa, Chikako, Onishi, Risa, Hirata, Jun, Hisaeda, Hajime
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470085/
https://www.ncbi.nlm.nih.gov/pubmed/26136736
http://dx.doi.org/10.3389/fmicb.2015.00600