iPSC-Based Models to Unravel Key Pathogenetic Processes Underlying Motor Neuron Disease Development

Motor neuron diseases (MNDs) are neuromuscular disorders affecting rather exclusively upper motor neurons (UMNs) and/or lower motor neurons (LMNs). The clinical phenotype is characterized by muscular weakness and atrophy leading to paralysis and almost invariably death due to respiratory failure. Ad...

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Detalles Bibliográficos
Autores principales: Faravelli, Irene, Frattini, Emanuele, Ramirez, Agnese, Stuppia, Giulia, Nizzardo, Monica, Corti, Stefania
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470174/
https://www.ncbi.nlm.nih.gov/pubmed/26237595
http://dx.doi.org/10.3390/jcm3041124

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470174/
https://www.ncbi.nlm.nih.gov/pubmed/26237595
http://dx.doi.org/10.3390/jcm3041124

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