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iPSC-Based Models to Unravel Key Pathogenetic Processes Underlying Motor Neuron Disease Development

Motor neuron diseases (MNDs) are neuromuscular disorders affecting rather exclusively upper motor neurons (UMNs) and/or lower motor neurons (LMNs). The clinical phenotype is characterized by muscular weakness and atrophy leading to paralysis and almost invariably death due to respiratory failure. Ad...

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Detalles Bibliográficos
Autores principales:	Faravelli, Irene, Frattini, Emanuele, Ramirez, Agnese, Stuppia, Giulia, Nizzardo, Monica, Corti, Stefania
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2014
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470174/ https://www.ncbi.nlm.nih.gov/pubmed/26237595 http://dx.doi.org/10.3390/jcm3041124

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