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Comparing ESC and iPSC—Based Models for Human Genetic Disorders

Traditionally, human disorders were studied using animal models or somatic cells taken from patients. Such studies enabled the analysis of the molecular mechanisms of numerous disorders, and led to the discovery of new treatments. Yet, these systems are limited or even irrelevant in modeling multipl...

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Detalles Bibliográficos
Autores principales: Halevy, Tomer, Urbach, Achia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470175/
https://www.ncbi.nlm.nih.gov/pubmed/26237596
http://dx.doi.org/10.3390/jcm3041146