PDGFRα signaling drives adipose tissue fibrosis by targeting progenitor cell plasticity

Fibrosis is a common disease process in which profibrotic cells disturb organ function by secreting disorganized extracellular matrix (ECM). Adipose tissue fibrosis occurs during obesity and is associated with metabolic dysfunction, but how profibrotic cells originate is still being elucidated. Here...

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Bibliographic Details
Main Authors: Iwayama, Tomoaki, Steele, Cameron, Yao, Longbiao, Dozmorov, Mikhail G., Karamichos, Dimitris, Wren, Jonathan D., Olson, Lorin E.
Format: Online Article Text
Language:English
Published: Cold Spring Harbor Laboratory Press 2015
Subjects:
Research Paper
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470280/
https://www.ncbi.nlm.nih.gov/pubmed/26019175
http://dx.doi.org/10.1101/gad.260554.115

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470280/
https://www.ncbi.nlm.nih.gov/pubmed/26019175
http://dx.doi.org/10.1101/gad.260554.115

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