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PDGFRα signaling drives adipose tissue fibrosis by targeting progenitor cell plasticity

Fibrosis is a common disease process in which profibrotic cells disturb organ function by secreting disorganized extracellular matrix (ECM). Adipose tissue fibrosis occurs during obesity and is associated with metabolic dysfunction, but how profibrotic cells originate is still being elucidated. Here...

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Detalles Bibliográficos
Autores principales:	Iwayama, Tomoaki, Steele, Cameron, Yao, Longbiao, Dozmorov, Mikhail G., Karamichos, Dimitris, Wren, Jonathan D., Olson, Lorin E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cold Spring Harbor Laboratory Press 2015
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470280/ https://www.ncbi.nlm.nih.gov/pubmed/26019175 http://dx.doi.org/10.1101/gad.260554.115

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