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Minishelterins separate telomere length regulation and end protection in fission yeast

The conserved shelterin complex is critical for chromosome capping and maintaining telomere length homeostasis. In fission yeast, shelterin is comprised of five proteins. Taz1, Rap1, and Poz1 function as negative regulators of telomere elongation, whereas Pot1 and Tpz1 are critical for end capping a...

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Detalles Bibliográficos
Autores principales: Pan, Lili, Hildebrand, Katie, Stutz, Cian, Thomä, Nicolas, Baumann, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470284/
https://www.ncbi.nlm.nih.gov/pubmed/26063574
http://dx.doi.org/10.1101/gad.261123.115