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A cell cycle-controlled redox switch regulates the topoisomerase IV activity

Topoisomerase IV (topo IV), an essential factor during chromosome segregation, resolves the catenated chromosomes at the end of each replication cycle. How the decatenating activity of the topo IV is regulated during the early stages of the chromosome cycle despite being in continuous association wi...

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Detalles Bibliográficos
Autores principales: Narayanan, Sharath, Janakiraman, Balaganesh, Kumar, Lokesh, Radhakrishnan, Sunish Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470285/
https://www.ncbi.nlm.nih.gov/pubmed/26063575
http://dx.doi.org/10.1101/gad.257030.114