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The androgen receptor confers protection against diet-induced atherosclerosis, obesity, and dyslipidemia in female mice

Androgens have important cardiometabolic actions in males, but their metabolic role in females is unclear. To determine the physiologic androgen receptor (AR)–dependent actions of androgens on atherogenesis in female mice, we generated female AR-knockout (ARKO) mice on an atherosclerosis-prone apoli...

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Detalles Bibliográficos
Autores principales: Fagman, Johan B., Wilhelmson, Anna S., Motta, Benedetta M., Pirazzi, Carlo, Alexanderson, Camilla, De Gendt, Karel, Verhoeven, Guido, Holmäng, Agneta, Anesten, Fredrik, Jansson, John-Olov, Levin, Malin, Borén, Jan, Ohlsson, Claes, Krettek, Alexandra, Romeo, Stefano, Tivesten, Åsa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470404/
https://www.ncbi.nlm.nih.gov/pubmed/25550469
http://dx.doi.org/10.1096/fj.14-259234