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Pyrimidine homeostasis is accomplished by directed overflow metabolism

Cellular metabolism converts available nutrients into usable energy and biomass precursors. The process is regulated to facilitate efficient nutrient use and metabolic homeostasis. Feedback inhibition of the first committed step of a pathway by its final product is a classical means of controlling b...

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Detalles Bibliográficos
Autores principales: Reaves, Marshall Louis, Young, Brian D., Hosios, Aaron M., Xu, Yi-Fan, Rabinowitz, Joshua D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470420/
https://www.ncbi.nlm.nih.gov/pubmed/23903661
http://dx.doi.org/10.1038/nature12445