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Pyrimidine homeostasis is accomplished by directed overflow metabolism
Cellular metabolism converts available nutrients into usable energy and biomass precursors. The process is regulated to facilitate efficient nutrient use and metabolic homeostasis. Feedback inhibition of the first committed step of a pathway by its final product is a classical means of controlling b...
Autores principales: | Reaves, Marshall Louis, Young, Brian D., Hosios, Aaron M., Xu, Yi-Fan, Rabinowitz, Joshua D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470420/ https://www.ncbi.nlm.nih.gov/pubmed/23903661 http://dx.doi.org/10.1038/nature12445 |
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