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Molecular Mechanism for the Thermo-Sensitive Phenotype of CHO-MT58 Cell Line Harbouring a Mutant CTP:Phosphocholine Cytidylyltransferase

Control and elimination of malaria still represents a major public health challenge. Emerging parasite resistance to current therapies urges development of antimalarials with novel mechanism of action. Phospholipid biosynthesis of the Plasmodium parasite has been validated as promising candidate ant...

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Detalles Bibliográficos
Autores principales: Marton, Lívia, Nagy, Gergely N., Ozohanics, Olivér, Lábas, Anikó, Krámos, Balázs, Oláh, Julianna, Vékey, Károly, Vértessy, Beáta G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470507/
https://www.ncbi.nlm.nih.gov/pubmed/26083347
http://dx.doi.org/10.1371/journal.pone.0129632