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First Demonstration of Antigen Induced Cytokine Expression by CD4-1(+) Lymphocytes in a Poikilotherm: Studies in Zebrafish (Danio rerio)
Adaptive immunity in homeotherms depends greatly on CD4+ Th cells which release cytokines in response to specific antigen stimulation. Whilst bony fish and poikilothermic tetrapods possess cells that express TcR and CD4-related genes (that exist in two forms in teleost fish; termed CD4-1 and CD4-2),...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470515/ https://www.ncbi.nlm.nih.gov/pubmed/26083432 http://dx.doi.org/10.1371/journal.pone.0126378 |