First Demonstration of Antigen Induced Cytokine Expression by CD4-1(+) Lymphocytes in a Poikilotherm: Studies in Zebrafish (Danio rerio)

Adaptive immunity in homeotherms depends greatly on CD4+ Th cells which release cytokines in response to specific antigen stimulation. Whilst bony fish and poikilothermic tetrapods possess cells that express TcR and CD4-related genes (that exist in two forms in teleost fish; termed CD4-1 and CD4-2),...

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Detalles Bibliográficos
Autores principales: Yoon, Sohye, Mitra, Suman, Wyse, Cathy, Alnabulsi, Ayham, Zou, Jun, Weerdenburg, Eveline M., M. van der Sar, Astrid, Wang, Difei, Secombes, Christopher J., Bird, Steve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470515/
https://www.ncbi.nlm.nih.gov/pubmed/26083432
http://dx.doi.org/10.1371/journal.pone.0126378

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