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Endothelial Alpha-Parvin Controls Integrity of Developing Vasculature and Is Required for Maintenance of Cell–Cell Junctions

RATIONALE: Angiogenesis and vessel integrity depend on the adhesion of endothelial cells (ECs) to the extracellular matrix and to adjacent ECs. The focal adhesion protein α-parvin (α-pv) is essential for vascular development. However, the role of α-pv in ECs in vivo is not known. OBJECTIVE: To deter...

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Detalles Bibliográficos
Autores principales: Fraccaroli, Alessia, Pitter, Bettina, Taha, Abdallah Abu, Seebach, Jochen, Huveneers, Stephan, Kirsch, Julian, Casaroli-Marano, Ricardo P., Zahler, Stefan, Pohl, Ulrich, Gerhardt, Holger, Schnittler, Hans-J., Montanez, Eloi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470528/
https://www.ncbi.nlm.nih.gov/pubmed/25925587
http://dx.doi.org/10.1161/CIRCRESAHA.117.305818