Emergent Stratification in Solid Tumors Selects for Reduced Cohesion of Tumor Cells: A Multi-Cell, Virtual-Tissue Model of Tumor Evolution Using CompuCell3D

Tumor cells and structure both evolve due to heritable variation of cell behaviors and selection over periods of weeks to years (somatic evolution). Micro-environmental factors exert selection pressures on tumor-cell behaviors, which influence both the rate and direction of evolution of specific beh...

Descripción completa

Detalles Bibliográficos
Autores principales: Swat, Maciej H., Thomas, Gilberto L., Shirinifard, Abbas, Clendenon, Sherry G., Glazier, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470639/
https://www.ncbi.nlm.nih.gov/pubmed/26083246
http://dx.doi.org/10.1371/journal.pone.0127972

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470639/
https://www.ncbi.nlm.nih.gov/pubmed/26083246
http://dx.doi.org/10.1371/journal.pone.0127972

Ejemplares similares