Cargando…

Emergent Stratification in Solid Tumors Selects for Reduced Cohesion of Tumor Cells: A Multi-Cell, Virtual-Tissue Model of Tumor Evolution Using CompuCell3D

Tumor cells and structure both evolve due to heritable variation of cell behaviors and selection over periods of weeks to years (somatic evolution). Micro-environmental factors exert selection pressures on tumor-cell behaviors, which influence both the rate and direction of evolution of specific beh...

Descripción completa

Detalles Bibliográficos
Autores principales:	Swat, Maciej H., Thomas, Gilberto L., Shirinifard, Abbas, Clendenon, Sherry G., Glazier, James A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470639/ https://www.ncbi.nlm.nih.gov/pubmed/26083246 http://dx.doi.org/10.1371/journal.pone.0127972

Ejemplares similares

Integrating Intracellular Dynamics Using CompuCell3D and Bionetsolver: Applications to Multiscale Modelling of Cancer Cell Growth and Invasion
por: Andasari, Vivi, et al.
Publicado: (2012)

3D Multi-Cell Simulation of Tumor Growth and Angiogenesis
por: Shirinifard, Abbas, et al.
Publicado: (2009)

Computer Simulations of Cell Sorting Due to Differential Adhesion
por: Zhang, Ying, et al.
Publicado: (2011)

Front Instabilities and Invasiveness of Simulated 3D Avascular Tumors
por: Poplawski, Nikodem J., et al.
Publicado: (2010)

Virtual-tissue computer simulations define the roles of cell adhesion and proliferation in the onset of kidney cystic disease
por: Belmonte, Julio M., et al.
Publicado: (2016)

The cell behavior ontology: describing the intrinsic biological behaviors of real and model cells seen as active agents
por: Sluka, James P., et al.
Publicado: (2014)

Adhesion Failures Determine the Pattern of Choroidal Neovascularization in the Eye: A Computer Simulation Study
por: Shirinifard, Abbas, et al.
Publicado: (2012)

A Liver-Centric Multiscale Modeling Framework for Xenobiotics
por: Sluka, James P., et al.
Publicado: (2016)

Objective Evaluation of a New Epidural Simulator by the CompuFlo(®) Epidural Instrument
por: Capogna, Giorgio, et al.
Publicado: (2018)

Modeling of xenobiotic transport and metabolism in virtual hepatic lobule models
por: Fu, Xiao, et al.
Publicado: (2018)

CAR-NK Cells in the Treatment of Solid Tumors
por: Wrona, Ewa, et al.
Publicado: (2021)

A Multi-cell, Multi-scale Model of Vertebrate Segmentation and Somite Formation
por: Hester, Susan D., et al.
Publicado: (2011)

Metastasis and Tumor Cell Migration of Solid Tumors
por: Hoeppner, Jens, et al.
Publicado: (2021)

Utilization of Circulating Tumor Cells in the Management of Solid Tumors
por: Kurniali, Peter C., et al.
Publicado: (2023)

The tumor vasculature an attractive CAR T cell target in solid tumors
por: Akbari, Parvin, et al.
Publicado: (2019)

Influence of the Tumor Microenvironment on NK Cell Function in Solid Tumors
por: Melaiu, Ombretta, et al.
Publicado: (2020)

Circulating Tumor Cells as Predictive and Prognostic Biomarkers in Solid Tumors
por: Capuozzo, Maurizio, et al.
Publicado: (2023)

Multiscale Modeling of Spheroid Tumors: Effect of Nutrient Availability on Tumor Evolution
por: Rosenbauer, Jakob, et al.
Publicado: (2023)

Using single-cell sequencing technology to detect circulating tumor cells in solid tumors
por: Xu, Jiasheng, et al.
Publicado: (2021)

Expression of chemokine receptors on circulating tumor cells in patients with solid tumors
por: Fusi, Alberto, et al.
Publicado: (2012)

Targeting Mitochondrial Function to Treat Quiescent Tumor Cells in Solid Tumors
por: Zhang, Xiaonan, et al.
Publicado: (2015)

The Tumor Invasion Paradox in Cancer Stem Cell-Driven Solid Tumors
por: Shyntar, Alexandra, et al.
Publicado: (2022)

The role of tumor microenvironment on cancer stem cell fate in solid tumors
por: Razi, Sara, et al.
Publicado: (2023)

Risk stratification for febrile neutropenia in patients with testicular germ cell tumors
por: Terbuch, Angelika, et al.
Publicado: (2018)

Risk stratification for venous thromboembolism in patients with testicular germ cell tumors
por: Bezan, Angelika, et al.
Publicado: (2017)

Intact Cohesion, Anaphase, and Chromosome Segregation in Human Cells Harboring Tumor-Derived Mutations in STAG2
por: Kim, Jung-Sik, et al.
Publicado: (2016)

Making CAR T Cells a Solid Option for Solid Tumors
por: Schmidts, Andrea, et al.
Publicado: (2018)

Correction to: Using single-cell sequencing technology to detect circulating tumor cells in solid tumors
por: Xu, Jiasheng, et al.
Publicado: (2022)

Cancer Stem Cells and Pediatric Solid Tumors
por: Friedman, Gregory K., et al.
Publicado: (2011)

Dendritic Cell-Based Immunotherapy for Solid Tumors()()
por: Jung, Nam-Chul, et al.
Publicado: (2018)

CAR T cells in solid tumors: challenges and opportunities
por: Marofi, Faroogh, et al.
Publicado: (2021)

Myeloid-Derived Suppressor Cells in Solid Tumors
por: Ma, Tianmiao, et al.
Publicado: (2022)

TCR engineered T cells for solid tumor immunotherapy
por: Zhang, Yikai, et al.
Publicado: (2022)

CAR T Cell Locomotion in Solid Tumor Microenvironment
por: Nguyen, Duy T., et al.
Publicado: (2022)

CAR T-Cell Therapy in Children with Solid Tumors
por: Kulczycka, Marika, et al.
Publicado: (2023)

The genetic landscape of the T cell non-inflamed tumor microenvironment in human solid tumors
por: Luke, Jason J, et al.
Publicado: (2015)

Tumor Microenvironment Immunosuppression: A Roadblock to CAR T-Cell Advancement in Solid Tumors
por: Johnson, Abigail, et al.
Publicado: (2022)

Expression of the Wilms' Tumor Gene WT1 in Solid Tumors and Its Involvement in Tumor Cell Growth
por: Oji, Yusuke, et al.
Publicado: (1999)

Current advances and challenges in CAR T-Cell therapy for solid tumors: tumor-associated antigens and the tumor microenvironment
por: Yan, Ting, et al.
Publicado: (2023)

Enhancing T cell persistence of CAR-redirected T cells in solid tumors
por: Guedan, Sonia, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_753dplscpfjbc9l7m96dpo73ig