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Deciphering Signaling Pathway Networks to Understand the Molecular Mechanisms of Metformin Action
A drug exerts its effects typically through a signal transduction cascade, which is non-linear and involves intertwined networks of multiple signaling pathways. Construction of such a signaling pathway network (SPNetwork) can enable identification of novel drug targets and deep understanding of drug...
| Autores principales: | , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470683/ https://www.ncbi.nlm.nih.gov/pubmed/26083494 http://dx.doi.org/10.1371/journal.pcbi.1004202 |