RSV-Induced H3K4 Demethylase KDM5B Leads to Regulation of Dendritic Cell-Derived Innate Cytokines and Exacerbates Pathogenesis In Vivo

Respiratory syncytial virus (RSV) infection can result in severe disease partially due to its ability to interfere with the initiation of Th1 responses targeting the production of type I interferons (IFN) and promoting a Th2 immune environment. Epigenetic modulation of gene transcription has been sh...

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Detalles Bibliográficos
Autores principales: Ptaschinski, Catherine, Mukherjee, Sumanta, Moore, Martin L., Albert, Mareike, Helin, Kristian, Kunkel, Steven L., Lukacs, Nicholas W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470918/
https://www.ncbi.nlm.nih.gov/pubmed/26083387
http://dx.doi.org/10.1371/journal.ppat.1004978

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4470918/
https://www.ncbi.nlm.nih.gov/pubmed/26083387
http://dx.doi.org/10.1371/journal.ppat.1004978

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