Nrf2 regulates ROS production by mitochondria and NADPH oxidase

BACKGROUND: Nuclear factor (erythroid-derived 2) factor 2 (Nrf2) is a crucial transcription factor mediating protection against oxidants. Nrf2 is negatively regulated by cytoplasmic Kelch-like ECH associated protein 1 (Keap1) thereby providing inducible antioxidant defence. Antioxidant properties of...

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Detalles Bibliográficos
Autores principales: Kovac, Stjepana, Angelova, Plamena R., Holmström, Kira M., Zhang, Ying, Dinkova-Kostova, Albena T., Abramov, Andrey Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Pub. Co 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471129/
https://www.ncbi.nlm.nih.gov/pubmed/25484314
http://dx.doi.org/10.1016/j.bbagen.2014.11.021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471129/
https://www.ncbi.nlm.nih.gov/pubmed/25484314
http://dx.doi.org/10.1016/j.bbagen.2014.11.021

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