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Biophysical Insights into How Spike Threshold Depends on the Rate of Membrane Potential Depolarization in Type I and Type II Neurons

Dynamic spike threshold plays a critical role in neuronal input-output relations. In many neurons, the threshold potential depends on the rate of membrane potential depolarization (dV/dt) preceding a spike. There are two basic classes of neural excitability, i.e., Type I and Type II, according to in...

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Detalles Bibliográficos
Autores principales: Yi, Guo-Sheng, Wang, Jiang, Tsang, Kai-Ming, Wei, Xi-Le, Deng, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471164/
https://www.ncbi.nlm.nih.gov/pubmed/26083350
http://dx.doi.org/10.1371/journal.pone.0130250