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Oral Delivery of a Novel Attenuated Salmonella Vaccine Expressing Influenza A Virus Proteins Protects Mice against H5N1 and H1N1 Viral Infection

Attenuated strains of invasive enteric bacteria, such as Salmonella, represent promising gene delivery agents for nucleic acid-based vaccines as they can be administrated orally. In this study, we constructed a novel attenuated strain of Salmonella for the delivery and expression of the hemagglutini...

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Detalles Bibliográficos
Autores principales: Pei, Zenglin, Jiang, Xiaohong, Yang, Zhu, Ren, Xiaoguang, Gong, Hao, Reeves, Michael, Sheng, Jingxue, Wang, Yu, Pan, Zishu, Liu, Fenyong, Wu, Jianguo, Lu, Sangwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471199/
https://www.ncbi.nlm.nih.gov/pubmed/26083421
http://dx.doi.org/10.1371/journal.pone.0129276