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Loss of Melanopsin Photoreception and Antagonism of the Histamine H3 Receptor by Ciproxifan Inhibit Light-Induced Sleep in Mice

Light has direct effects on sleep and wakefulness causing arousal in diurnal animals and sleep in nocturnal animals. In the present study, we assessed the modulation of light-induced sleep by melanopsin and the histaminergic system by exposing mice to millisecond light flashes and continuous light r...

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Detalles Bibliográficos
Autores principales: Muindi, Fanuel, Colas, Damien, Ikeme, Jesse, Ruby, Norman F., Heller, H. Craig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471207/
https://www.ncbi.nlm.nih.gov/pubmed/26083020
http://dx.doi.org/10.1371/journal.pone.0128175