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Revealing Pathway Dynamics in Heart Diseases by Analyzing Multiple Differential Networks

Development of heart diseases is driven by dynamic changes in both the activity and connectivity of gene pathways. Understanding these dynamic events is critical for understanding pathogenic mechanisms and development of effective treatment. Currently, there is a lack of computational methods that e...

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Detalles Bibliográficos
Autores principales: Ma, Xiaoke, Gao, Long, Karamanlidis, Georgios, Gao, Peng, Lee, Chi Fung, Garcia-Menendez, Lorena, Tian, Rong, Tan, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471235/
https://www.ncbi.nlm.nih.gov/pubmed/26083688
http://dx.doi.org/10.1371/journal.pcbi.1004332