Tramadol and Tramadol+Caffeine Synergism in the Rat Formalin Test Are Mediated by Central Opioid and Serotonergic Mechanisms

Different analgesic combinations with caffeine have shown this drug to be capable of increasing the analgesic effect. Many combinations with nonsteroidal anti-inflammatory drugs (NSAIDs) have been carried out, but, in regard to opioids, only combinations with morphine and tramadol have been reported...

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Detalles Bibliográficos
Autores principales: Carrillo-Munguía, Norma, González-Trujano, Ma. Eva, Huerta, Miguel, Trujillo, Xochitl, Díaz-Reval, M. Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471251/
https://www.ncbi.nlm.nih.gov/pubmed/26146627
http://dx.doi.org/10.1155/2015/686424

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471251/
https://www.ncbi.nlm.nih.gov/pubmed/26146627
http://dx.doi.org/10.1155/2015/686424

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