The autism-associated gene chromodomain helicase DNA-binding protein 8 (CHD8) regulates noncoding RNAs and autism-related genes

Chromodomain helicase DNA-binding protein 8 (CHD8) was identified as a leading autism spectrum disorder (ASD) candidate gene by whole-exome sequencing and subsequent targeted-sequencing studies. De novo loss-of-function mutations were identified in 12 individuals with ASD and zero controls, accounti...

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Detalles Bibliográficos
Autores principales: Wilkinson, B, Grepo, N, Thompson, B L, Kim, J, Wang, K, Evgrafov, O V, Lu, W, Knowles, J A, Campbell, D B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471293/
https://www.ncbi.nlm.nih.gov/pubmed/25989142
http://dx.doi.org/10.1038/tp.2015.62

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471293/
https://www.ncbi.nlm.nih.gov/pubmed/25989142
http://dx.doi.org/10.1038/tp.2015.62

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