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Toxoplasma Actin Is Required for Efficient Host Cell Invasion

Apicomplexan parasites actively invade host cells using a mechanism predicted to be powered by a parasite actin-dependent myosin motor. In the model apicomplexan Toxoplasma gondii, inducible knockout of the actin gene, ACT1, was recently demonstrated to limit but not completely abolish invasion. Thi...

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Detalles Bibliográficos
Autores principales: Drewry, Lisa L., Sibley, L. David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471557/
https://www.ncbi.nlm.nih.gov/pubmed/26081631
http://dx.doi.org/10.1128/mBio.00557-15