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Genetic Stabilization of the Drug-Resistant PMEN1 Pneumococcus Lineage by Its Distinctive DpnIII Restriction-Modification System

The human pathogen Streptococcus pneumoniae (pneumococcus) exhibits a high degree of genomic diversity and plasticity. Isolates with high genomic similarity are grouped into lineages that undergo homologous recombination at variable rates. PMEN1 is a pandemic, multidrug-resistant lineage. Heterologo...

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Detalles Bibliográficos
Autores principales: Eutsey, Rory A., Powell, Evan, Dordel, Janina, Salter, Susannah J., Clark, Tyson A., Korlach, Jonas, Ehrlich, Garth D., Hiller, N. Luisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471560/
https://www.ncbi.nlm.nih.gov/pubmed/26081630
http://dx.doi.org/10.1128/mBio.00173-15