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Cyclic Rhamnosylated Elongation Factor P Establishes Antibiotic Resistance in Pseudomonas aeruginosa

Elongation factor P (EF-P) is a ubiquitous bacterial protein that is required for the synthesis of poly-proline motifs during translation. In Escherichia coli and Salmonella enterica, the posttranslational β-lysylation of Lys34 by the PoxA protein is critical for EF-P activity. PoxA is absent from m...

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Detalles Bibliográficos
Autores principales: Rajkovic, Andrei, Erickson, Sarah, Witzky, Anne, Branson, Owen E., Seo, Jin, Gafken, Philip R., Frietas, Michael A., Whitelegge, Julian P., Faull, Kym F., Navarre, William, Darwin, Andrew J., Ibba, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471567/
https://www.ncbi.nlm.nih.gov/pubmed/26060278
http://dx.doi.org/10.1128/mBio.00823-15