Target-Based Whole-Cell Screening by (1)H NMR Spectroscopy**

An NMR-based approach marries the two traditional screening technologies (phenotypic and target-based screening) to find compounds inhibiting a specific enzymatic reaction in bacterial cells. Building on a previous study in which it was demonstrated that hydrolytic decomposition of meropenem in livi...

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Detalles Bibliográficos
Autores principales: Ma, Junhe, Cao, Qing, McLeod, Sarah M, Ferguson, Keith, Gao, Ning, Breeze, Alexander L, Hu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2015
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471574/
https://www.ncbi.nlm.nih.gov/pubmed/25693499
http://dx.doi.org/10.1002/anie.201410701

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471574/
https://www.ncbi.nlm.nih.gov/pubmed/25693499
http://dx.doi.org/10.1002/anie.201410701

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