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trans-Hydrogenation: Application to a Concise and Scalable Synthesis of Brefeldin A**

The important biochemical probe molecule brefeldin A (1) has served as an inspirational target in the past, but none of the many routes has actually delivered more than just a few milligrams of product, where documented. The approach described herein is clearly more efficient; it hinges upon the fir...

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Detalles Bibliográficos
Autores principales: Fuchs, Michael, Fürstner, Alois
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471581/
https://www.ncbi.nlm.nih.gov/pubmed/25651519
http://dx.doi.org/10.1002/anie.201411618