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MicroRNA-34a suppresses the breast cancer stem cell-like characteristics by downregulating Notch1 pathway

MicroRNAs play pivotal roles in cancer stem cell regulation. Previous studies have shown that microRNA-34a (miR-34a) is downregulated in human breast cancer. However, it is unknown whether and how miR-34a regulates breast cancer stem cells. Notch signaling is one of the most important pathways in st...

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Detalles Bibliográficos
Autores principales: Kang, Le, Mao, Jun, Tao, Yajun, Song, Bo, Ma, Wei, Lu, Ying, Zhao, Lijing, Li, Jiazhi, Yang, Baoxue, Li, Lianhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471794/
https://www.ncbi.nlm.nih.gov/pubmed/25783790
http://dx.doi.org/10.1111/cas.12656