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Targeting the canonical Wnt/β-catenin pathway in hematological malignancies

The canonical Wnt/β-catenin pathway plays an important role in different developmental processes through the regulation of stem cell functions. In the activation of the canonical Wnt/β-catenin pathway, β-catenin protein is imported into the nucleus and activates transcription of target genes includi...

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Detalles Bibliográficos
Autores principales: Ashihara, Eishi, Takada, Tetsuya, Maekawa, Taira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471797/
https://www.ncbi.nlm.nih.gov/pubmed/25788321
http://dx.doi.org/10.1111/cas.12655