A CRISPR/Cas-Mediated Selection-free Knockin Strategy in Human Embryonic Stem Cells

The development of new gene-editing tools, in particular the CRISPR/Cas system, has greatly facilitated site-specific mutagenesis in human embryonic stem cells (hESCs), including the introduction or correction of patient-specific mutations for disease modeling. However, integration of a reporter gen...

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Detalles Bibliográficos
Autores principales: Zhu, Zengrong, Verma, Nipun, González, Federico, Shi, Zhong-Dong, Huangfu, Danwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Resource
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471821/
https://www.ncbi.nlm.nih.gov/pubmed/26028531
http://dx.doi.org/10.1016/j.stemcr.2015.04.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471821/
https://www.ncbi.nlm.nih.gov/pubmed/26028531
http://dx.doi.org/10.1016/j.stemcr.2015.04.016

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