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Efficient Generation of Cardiac Purkinje Cells from ESCs by Activating cAMP Signaling
Dysfunction of the specialized cardiac conduction system (CCS) is associated with life-threatening arrhythmias. Strategies to derive CCS cells, including rare Purkinje cells (PCs), would facilitate models for mechanistic studies and drug discovery and also provide new cellular materials for regenera...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471825/ https://www.ncbi.nlm.nih.gov/pubmed/26028533 http://dx.doi.org/10.1016/j.stemcr.2015.04.015 |