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Efficient Generation of Cardiac Purkinje Cells from ESCs by Activating cAMP Signaling
Dysfunction of the specialized cardiac conduction system (CCS) is associated with life-threatening arrhythmias. Strategies to derive CCS cells, including rare Purkinje cells (PCs), would facilitate models for mechanistic studies and drug discovery and also provide new cellular materials for regenera...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471825/ https://www.ncbi.nlm.nih.gov/pubmed/26028533 http://dx.doi.org/10.1016/j.stemcr.2015.04.015 |