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Human Germline: A New Research Frontier

We recently elucidated the mechanism of human primordial germ cell (hPGC) specification and resetting of the epigenome for totipotency. The regulators of hPGC specification also initiate resetting of the epigenome, leading to a comprehensive erasure of DNA methylation, erasure of imprints and X reac...

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Detalles Bibliográficos
Autor principal: Surani, M. Azim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471826/
https://www.ncbi.nlm.nih.gov/pubmed/26028529
http://dx.doi.org/10.1016/j.stemcr.2015.04.014