Expression of α-Smooth Muscle Actin Determines the Fate of Mesenchymal Stromal Cells

Pro-fibrotic microenvironments of scars and tumors characterized by increased stiffness stimulate mesenchymal stromal cells (MSCs) to express α-smooth muscle actin (α-SMA). We investigated whether incorporation of α-SMA into contractile stress fibers regulates human MSC fate. Sorted α-SMA-positive M...

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Detalles Bibliográficos
Autores principales: Talele, Nilesh P., Fradette, Julie, Davies, John E., Kapus, Andras, Hinz, Boris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471834/
https://www.ncbi.nlm.nih.gov/pubmed/26028530
http://dx.doi.org/10.1016/j.stemcr.2015.05.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471834/
https://www.ncbi.nlm.nih.gov/pubmed/26028530
http://dx.doi.org/10.1016/j.stemcr.2015.05.004

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