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Expression of α-Smooth Muscle Actin Determines the Fate of Mesenchymal Stromal Cells
Pro-fibrotic microenvironments of scars and tumors characterized by increased stiffness stimulate mesenchymal stromal cells (MSCs) to express α-smooth muscle actin (α-SMA). We investigated whether incorporation of α-SMA into contractile stress fibers regulates human MSC fate. Sorted α-SMA-positive M...
Autores principales: | Talele, Nilesh P., Fradette, Julie, Davies, John E., Kapus, Andras, Hinz, Boris |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471834/ https://www.ncbi.nlm.nih.gov/pubmed/26028530 http://dx.doi.org/10.1016/j.stemcr.2015.05.004 |
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