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Retrograde regulation of STIM1-Orai1 interaction and store-operated Ca(2+) entry by calsequestrin

Interaction between the endoplasmic reticulum (ER)-located stromal interaction molecue1 (STIM1) and the plasma membrane-located Ca(2+) channel subunit, Orai1, underlies store-operated Ca(2+) entry (SOCE). Calsequestrin1 (CSQ1), a sarcoplasmic reticulum Ca(2+) buffering protein, inhibits SOCE, but th...

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Detalles Bibliográficos
Autores principales: Wang, Limin, Zhang, Lane, Li, Shu, Zheng, Yuanyuan, Yan, Xinxin, Chen, Min, Wang, Haoyang, Putney, James W., Luo, Dali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471903/
https://www.ncbi.nlm.nih.gov/pubmed/26087026
http://dx.doi.org/10.1038/srep11349