Cargando…
Human POLD1 modulates cell cycle progression and DNA damage repair
BACKGROUND: The activity of eukaryotic DNA polymerase delta (Pol δ) plays an essential role in genome stability through its effects on DNA replication and repair. The p125 catalytic subunit of Pol δ is encoded by POLD1 gene in human cells. To clarify biological functions of POLD1, we investigated th...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471906/ https://www.ncbi.nlm.nih.gov/pubmed/26087769 http://dx.doi.org/10.1186/s12858-015-0044-7 |